HPHY 621: Advanced overview of neural physiology, neural control of human movement, and the biomechanical constraints underlying that control. The objective of this series of courses (HPHY 621, 622, 623) is to provide a scientific foundation for the study of human physiology at the graduate level. This course will consider in depth the mechanisms underlying the neural control of human movement and the biomechanical constraints that are inherent in the human body. The anatomical and neurophysiological characteristics of different sensorimotor structures in the brain will be discussed. In addition, the forces acting at different joints in the body and the resulting kinematic characteristics resulting from those forces will be considered.
HPHY 413/513: Physiologic basis for skeletal muscle adaptation to increased and decreased use and injury. Emphasizes how structure dictates function relevant to rehabilitation. This course will cover skeletal muscle cell/tissue physiology with a focus on adaptation to increased and decreased use, and response to injury using experimental conditions that demonstrate how structure dictates function. Chapter 1 will cover muscle development and anatomy as the significance of structure throughout the course. Chapter 2 will focus on mechanical and physiological properties of skeletal muscle, including muscle structure-functional relationships and neuromuscular system. Chapter 3 focuses on the way muscles, tendons, and joints interact to produce movement and integrate the information form chapters 1 and 2. Chapter 4 presents various models of increased use and detailing the various cellular responses to experimental conditions resulting in adaptive change to ‘increased use.’ Chapter 5 describes models of decreased use and how muscle cells adapt. Chapter 6 will cover the response to injury and integrate clinical manifestations of increased, decreased use with injury response, i.e., Ch 4-6. Relevant journal articles will be integrated with chapters 4-6 that will emphasize rehabilitation and biomedical application. Prereqs apply. Restricted to HPHY majors.